Key Definitions: SFI vs. FCOI

A significant financial interest (SFI) is defined by the PHS criteria on subsection Significant Financial Interest (SFI)
- All PHS Investigators must disclose all SFIs
A Significant Financial Interest (SFI) is not always an FCOI
The designated Institutional official determines if an FCOI exists when a SFI could directly and significantly affect the design, conduct, or reporting of the PHS-funded research